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Leinco Technologies Inc Anti-Mouse NK1.1 (Natural Killer Cells, KR-P1C, NKR-P1B, Ly-55, CD161b, CD161c) In Vivo GOLD; Clone PK136; Isotype: Mouse IgG2a κ

Supplier: Leinco Technologies Inc N1231.0 MG

Specificity: Clone PK136 recognizes mouse NK1.1. Antigen Distribution: NK-1.1 is encoded by the NKR-P1B/NKR-P1C gene and expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Background: Both the lysis of tumor cells In vitro and rejection of bone marrow allografts In vivo have been correlated with the expression of NK-1.1(NKR-P1C). NK-1.1 and DX5 are regularly used as mouse NK cell markers. Applications: (IP, WB, B) Proliferation of a subset of NK cells can be induced when combining plate-bound PK136 with low concentrations of IL-2. Leinco’s In vivo GOLDTM and In vivo PLATINUMTM functional antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
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