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AdipoGen anti-NLRP3/NALP3, mAb (Cryo-2) Monoclonal Antibody
SDP

Supplier:  AdipoGen AG20B0014C100

Encompass_Preferred

anti-NLRP3/NALP3, mAb (Cryo-2), AdipoGen Life Sciences. Monoclonal Antibody. Recognizes mouse and human NLRP3/NALP3. Isotype: Mouse IgG2b. Clone: Cryo-2. Applications: IHC, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).

Catalog No. 50-463-385


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