Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical ANTIBODY ABT-639 1mg
Supplier: Cayman Chemical 287421 MG
A T-type calcium channel blocker; inhibits inactivated-state Cav3.2 channels (IC50 = 2.3 μM) and inactivated-state Cav3.1 and Cav3.3 channels by 50 and 39%, respectively, at 10 μM; selectively inhibits inactivated-state T-type calcium currents over resting-state currents in rat DRG neurons (IC50s = 7.6 and >30 μM, respectively); reverses the hind limb grip force deficit in a rat model of MIA-induced osteoarthritic pain (ED50 = 2 mg/kg); dose-dependently increases the paw withdrawal threshold in rat SNL and CCI models of neuropathic pain; attenuates cold allodynia in the CCI rat model at ≥3 mg/kg
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?