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Cayman Chemical ANTIBODY ADH-1 5mg

Supplier: Cayman Chemical 299815 MG
A cyclic peptide antagonist of N-cadherin; inhibits neurite outgrowth in cerebellar neurons cultured on N-cadherin-expressing 3T3 cell monolayers (IC50 = 0.323 mM); inhibits cell scattering and motility induced by collagen I in Capan-1 cells and wild-type and N-cadherin-overexpressing BxPC-3 cells at 0.2 mg/ml; induces apoptosis in N-cadherin-overexpressing, but not knockdown, BxPC-3 at 1 mg/ml; reduces tumor growth in an N-cadherin-overexpressing BxPC-3 mouse xenograft model at 50 mg/kg
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