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Cayman Chemical ANTIBODY AmcasertIb 1mg
SDP

Supplier:  Cayman Chemical 229801 MG

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An inhibitor of cancer stem cells; inhibits the growth of HT-29 and MDA-MB-231 cancer cells (IC50s = 100-250 nM for both); exhibits a 2-fold increase in potency for a population of SW480 cells enriched for CSCs; reduces spherogenesis of CD44+-enriched FaDu cells; reduces tumor growth in PC3, HepG2, FaDu, and MKN45 mouse xenograft models when administered orally at a dose of 100 mg/kg; inhibits EGFR, C-MET, HER2, and PDGFRα in vitro without reducing global tyrosine kinase activity

Catalog No. 50-296-4438


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