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Cayman Chemical ANTIBODY ApremIlast 25mg

Supplier: Cayman Chemical 1850225 MG
An orally active inhibitor of PDE4 with an IC50 value of 74 nM when tested in U937 cell lysates with 1 mM cAMP; decreases epidermal thickness in a mouse model of psoriasis, reduces both TNF-α and MMP-3 production in gut cells from patients with IBD, and improves clinical score in mouse models of arthritis
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