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Cayman Chemical ANTIBODY APY-29 10mg
SDP

Supplier:  Cayman Chemical 2291310 MG

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A modulator of IRE1α function; binds to the ATP-binding site on IRE1α, where it inhibits autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM); restores the ability of dephosphoylated IRE1α to cleave XBP1 mRNA in a dose-dependent manner; enhances IRE1α oligomerization in a crosslinking assay

Numéro de catalogue. 50-299-3971


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