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Cayman Chemical ANTIBODY ARS1620 1mg
Supplier: Cayman Chemical 279151 MG
A covalent inhibitor of K-RASG12C (IC50 = G12C (IC50s = 150 nM) over various cells expressing wild-type K-RAS (IC50s = >10 μM); induces tumor regression in a MIA-PaCa2 mouse xenograft model at 200 mg/kg; decreases tumor volume in K-RASG12C-expressing PDX mouse models
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