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Cayman Chemical ANTIBODY Atovaquon 50mg
Supplier: Cayman Chemical 2380250 MG
An antiprotozoal agent; inhibits complex III activity on dihydroorotate in isolated P. falciparum and P. yoelii mitochondria more potently than in rat liver mitochondria (EC50s = 0.95, 0.94, and 510 nM, respectively); depolarizes the mitochondrial membrane in P. yoelii-infected mouse erythrocytes (EC50 = 260 nM); inhibits human BCRP- and P-glycoprotein-mediated transport in membrane vesicles (IC50s = 0.23 and 6.8 μM, respectively); inhibits the growth of T. gondii in MRC-5 human lung fibroblasts in vitro (IC50 = ~64 nM); increases mean survival of T. gondii-infected mice from 5.5 to 21.2 days (100 mg/kg per day)
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