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Cayman Chemical ANTIBODY AVE-0991 10mg
Supplier: Cayman Chemical 3783710 MG
A Mas receptor agonist; binds to the Mas receptor in bovine aortic endothelial cell membranes and COS cells (IC50s = 21 and 47.5 nM, respectively); inhibits perivascular inflammation and increases plaque stability in an ApoE-/- mouse model of atherosclerosis at 0.58 µmol/kg per day; inhibits the formation of angiotensin II-induced abdominal aortic aneurysm in ApoE-/- mice
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