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Cayman Chemical ANTIBODY AZ 32 1mg
Supplier: Cayman Chemical 263801 MG
An ATM kinase inhibitor (IC50 = 50s = 4.6 and >4.6 µM, respectively); enhances radiation-induced cytotoxicity in a panel of five human glioma cells expressing wild-type or mutant p53; increases survival in a U87-281G glioma orthotopic mouse xenograft model, as well as a NCI H2228 NSCLC mouse xenograft model of metastatic brain tumors, at 200 and 50 mg/kg, respectively, in combination with ionizing radiation
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