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Cayman Chemical ANTIBODY AZ 7371 5mg

Supplier: Cayman Chemical 193105 MG
A non-covalent inhibitor of bacterial DprE1; inhibits wild-type M. smegmatis DprE1 and DprE1C394G (IC50 = 0.01 µM for both) but not DprE1Y321H (IC50 = >10 µM); active against wild-type M. tuberculosis DprE1 (MIC = 1.56 µM) and DprE1C387S or DprE1C387G (MICs = 0.39 and 0.78 µM, respectively) but not DprE1Y314H (MIC = >200 µM); selective for these targets over Gram-positive and Gram-negative bacteria but does inhibit phosphodiesterase 6 (PDE6; IC50 = 4 µM)
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