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Cayman Chemical ANTIBODY AZD 0095 5mg

Supplier: Cayman Chemical 421345 MG
An MCT4 inhibitor (IC50 = 1.3 nM); selectively inhibits lactate influx in NCI H358 cells (IC50 = 6.1 nM), which highly express MCT4 and do not express MCT1, over lactate influx in K562 cells (IC50 = >30 µM), which highly express MCT1 and do not express MCT4; inhibits the proliferation of NCI H358 cells (IC50 = 26 nM); reduces tumor growth in an NCI H358 mouse xenograft model at 100 mg/kg twice per day in combination with cediranib
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