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Cayman Chemical ANTIBODY BAR501 5mg
Supplier: Cayman Chemical 224605 MG
A selective GP-BAR1 agonist (EC50 = 1 μM); reduces hepatic perfusion pressure and counteracts norepinephrine-induced vasoconstriction in naïve rats; protects against development of endothelial dysfunction by increasing CSE expression and activity and reducing ET-1 gene expression in rat model of cirrhosis; increases Akt-dependent phosphorylation of CSE and eNOS and inhibits ET-1 transcription in vitro; reduces trinitrobenzenesulfonic acid-induced colitis in mice in a dose-dependent manner
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