Cayman Chemical ANTIBODY BD 750 100mg

Supplier:  Cayman Chemical 37574100 MG

An immunosuppressant; inhibits the proliferation of primary human and mouse T cells (IC50s = 1.1 and 1.5 µM, respectively) without inducing cytotoxicity at 3.13 to 50 µM; induces cell cycle arrest at the G0/G1 phases in activated primary human T cells at 0.625, 2.5, and 10 µM; decreases cyclin D3 and Cdk6 levels in activated primary mouse T cells at 2.5 and 10 µM; reduces the proliferation of IL-2-stimulated CTLL mouse T cells (IC50 = 1.2 µM) and decreases phosphorylated Stat5 levels in the same cells at 5 and 20 µM; inhibits 2,4-dinitrofluorobenzene-induced increases in EAr thickness and EAr patch weight in a mouse model of delayed-type hypersensitivity

Catalog No. 50-291-5802