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Cayman Chemical ANTIBODY BDP9066 5mg
Supplier: Cayman Chemical 262645 MG
An inhibitor of MRCKα and MRCKβ (Kis = 0.0136 and 0.0233 nM, respectively); selective for MRCKα and MRCKβ over ROCK1 and ROCK2 (Kis = 18.4 and 5.38 nM, respectively) and a panel of 115 additional kinases at 1 µM; has antiproliferative activity against a panel of 757 cancer cell lines (EC50s = 50 = 64 nM); inhibits the motility of SCC-12 cells; decreases average papilloma volume in a mouse two-stage model of DMBA-initiated and TPA-promoted skin carcinogenesis at 25 UG/animal
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