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Cayman Chemical ANTIBODY BIndarIt 25mg
Supplier: Cayman Chemical 1147925 MG
An inhibitor of MCP production; selective for MCP-1/CCL2, MPC-3/CCL7, and MCP-2/CCL8; inhibits LPS- or C. albicans-induced production of MCP-1/CCL2 in isolated human monocytes (IC50s = 172 and 403 µM, respectively); delays the onset of proteinuria and prolongs survival in a mouse model of experimental lupus nephritis at 50 mg/kg; prevents LPS-induced increases in MCP-1/CCL2 expression in mouse brain and spinal cord when administered at a dose of 200 mg/kg; a noncompetitive inhibitor of MCT4 (Ki = 30.2 µM) that is selective for MCT4 over MCT1
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