Cayman Chemical ANTIBODY BIthIonl 50g

Supplier:  Cayman Chemical 2184450 G

An anthelmintic agent; a NAPE-PLD antagonist (IC50 = 2.1 µM); selective for NAPE-PLD over LPL and CA (IC50s = 46 and 178 µM, respectively); inhibits efferocytosis in primary mouse BMDMs at 10 µM; inhibits TNF-α-induced NF-κB transcriptional activity in a reporter assay using HEK293 cells (IC50 = 11.2 µM); inhibits caspase-3 activity by 90% in a cell-free assay at 33 µM and prevents diphtheria toxin-, cholera toxin-, or P. aeruginosa exotoxin A-induced death in RAW 264.7 macrophages at the same concentration; inhibits the replication of Zika virus in primary human astrocytes and Vero E6 cells (EC50s = 5.5 and 6.3 µM, respectively); decreases the number of G. salaris helminths in G. salaris-infected O. mykiss without inducing toxicity at 12.5 or 20 mg/L

Catalog No. 50-298-5996