Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical ANTIBODY BLU-285 25mg
Supplier: Cayman Chemical 2298525 MG
A dual inhibitor of KIT and PDGFRα mutant kinases (IC50s = 0.27 and 0.24 nM for KITD816V and PDGFRαD842V, respectively); >150-fold selective for KITD816V and PDGFRαD842V over a kinase panel at a concentration of 3 μM; has activity against a panel of KIT and PDGFRα loop mutants identified in patients with GISTs (IC50s = D814Y mastocytoma allograft mouse model and a GIST patient-derived mouse xenograft model in a dose-dependent manner when administered at doses ranging from 0.3-30 mg/kg
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?