Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical ANTIBODY BMS 986260 10mg
Supplier: Cayman Chemical 4204210 MG
An ALK5 inhibitor (IC50 = 0.0015 µM); selective for ALK over TGF-βRII (IC50 = > 15 µM) and a panel of 213 additional kinases at 1 µM; inhibits TGF-β-induced increases in the nuclear translocation of phosphorylated SMAD2/3 in Mv 1 Lu cells (IC50 = 0.35 µM); decreases tumor growth in an MC-38 murine colon carcinoma model of tumor rechallenge at 3.75 mg/kg per day in combination with an antibody against PD-1; induces hyperproliferation of chondrocytes in the femoral epiphysis, thickening of the cardiac atrioventricular valve, and inflammation in the aortic vasculature in rats at 10 mg/kg per day
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?