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Cayman Chemical ANTIBODY BPN14770 10mg

Supplier: Cayman Chemical 3407510 MG
A PDE4D inhibitor; selectively inhibits dimeric PDE4DS129D and PDE4DS54D over wild-type dimeric PDE4D, dimeric PDE4DS133D, and monomeric PDE4D2 (IC50s = 7.8, 7.4, 1,018, 2,013, and 127 nM, respectively); enhances novel object discrimination in mice from 0.3-30 mg/kg; decreases hyperarousal and increases social interaction time, indicating anxiolytic-like activity, nesting, and marble-burying behavior in the Fmr1-/- mouse model of fragile X syndrome at 0.3 mg/kg
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