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Cayman Chemical ANTIBODY BTZ043 10mg
Supplier: Cayman Chemical 2293010 MG
An antibiotic with antimycobacterial activity; targets mycobacterial cell wall synthesis by inhibiting DprE1; active against various Mycobacterium species in vitro, including M. smegmatis, M. bovis, and M. tuberculosis (MICs = 4, 2, and 1 ng/ml, respectively), as well as the actinobacterium N. brasiliensis (MIC50 = 0.125 μg/ml); active against M. tuberculosis in RAW 264.7 murine macrophages (MIC = M. tuberculosis cells in lung and spleen in a mouse model of chronic tuberculosis infection at 37.5 or 300 mg/kg for four weeks
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