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Cayman Chemical ANTIBODY BVT 14225 1mg

Supplier: Cayman Chemical 412241 MG
An 11β-HSD1 inhibitor (IC50s = 52 and 284 for the human and mouse enzymes, respectively); selective for human 11β-HSD1 over human 11β-HSD2 (IC50 = >10,000 nM); inhibits 11β-HSD1 by 55% in HEK293 cells expressing human HSD11B1 at 10 µM; reduces blood glucose levels in a rat model of streptozotocin- and nicotinamide-induced diabetes at 50 mg/kg
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