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Cayman Chemical ANTIBODY C-178 5mg
Supplier: Cayman Chemical 258605 MG
A STING inhibitor; binds to Cys91 on STING to block its and prevents recruitment and phosphorylation of TBK1 in HEK293T cells; selectively reduces STING-, but not RIG-I- or TBK1-, mediated IFN-β reporter activity in HEK293 cells from 0.01-1.25 µM; prevents increases in Ifnb1 expression induced by cyclic di-GMP, double-stranded DNA, and LPS in BMDMs at 0.5 µM
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