Cayman Chemical ANTIBODY CytarabIn 500mg

Supplier:  Cayman Chemical 16069500 MG

A nucleoside analog and prodrug form of ara-CTP; triphosphorylated to ara-CTP by the successive actions of deoxycytidine kinase, deoxycytidylate kinase, and nucleoside diphosphate kinase; inhibits proliferation of HL-60, ML-1, Raji, and Jurkat human leukemia cell lines (IC50s = 37, 17, 16, and 72 nM, respectively); induces cell cycle arrest at the G0/G1 phase in HL-60 cells at 2.5 and 15 µM; reduces tumor growth and increases tumor caspase-3 activity in an MOLM-13 mouse xenograft model at 75 mg/kg per day intraperitoneally; increases survival and reduces brain herpesvirus titers in infected rats at 80 and 320 mg/kg subcutaneously

Catalog No. 50-297-2127