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Cayman Chemical ANTIBODY Erteberel 5mg
Supplier: Cayman Chemical 221305 MG
An ERβ agonist; selective for ERβ over ERα in reporter assays using PC3 cells expressing the human receptors (EC50s = 0.66 and 19.4 nM, respectively); induces apoptosis and cell cycle arrest at the G2/M phase in U87MG and U251 cells at 5 µM; enhances cisplatin-, lomustine-, or bleomycin-induced cytotoxicity in U251 cells at 1 µM; reduces tumor growth in a U251 orthotopic model of glioblastoma in ovariectomized mice at 5 mg/kg; decreases prostate weight in a mouse model of BPH at 0.01, 0.025, and 0.05 mg/kg
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