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Cayman Chemical ANTIBODY FDW028 25mg
Supplier: Cayman Chemical 3954325 MG
A FUC8 inhibitor; binds to FUC8 (Kd = 5.486 µM) and inhibits core fucosylation in HCT-8 and SW480 CRC cells; induces degradation of B7-H3 via CMA in the same cells at 50 µM; reduces tumor volume and increases survival in an SW480 mouse xenograft model at 10 and 20 mg/kg
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