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Cayman Chemical ANTIBODY GAT229 10mg
SDP

Supplier:  Cayman Chemical 2448610 MG

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An allosteric modulator of the CB1 receptor; the S-(–) enantiomer of GAT211; enhances the binding of CP 55,940 to CHO cells expressing hCB1 by 130% at 1 μM; enhances the activity of 2-AG, AEA, and CP 55,940 in arrestin2, as well as ERK1/2 and PLCβ3 phosphorylation, assays to HEK293 cells expressing hCB1; enhances depolarization-induced suppression of excitation but does not inhibit excitatory postsynaptic currents in murine autaptic hippocampal neurons at 1 μM; reduces intraocular pressure by 5.8 and 7.7 mm Hg after 6 and 12 hours, respectively, in a nee transgenic mouse model of ocular hypertension at 0.2%, topical

Catalog No. 50-293-5558


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