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Cayman Chemical ANTIBODY GDC-0575 25mg
SDP

Supplier:  Cayman Chemical 3430025 MG

Encompass_Preferred

A Chk1 inhibitor (IC50 = 1.2 nM); >30-fold selective for Chk1 over a panel of more than 450 wild-type and mutant kinases; enhances cytarabine-induced apoptosis in HL-60, KG-1, U937, and ML-1 AML cells; nearly completely eliminates tumor burden in AML PDX mouse models at 7.5 mg/kg in combination with cytarabine

Catalog No. 50-294-8151


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