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Cayman Chemical ANTIBODY Gn-6640 25mg
SDP

Supplier:  Cayman Chemical 3375125 MG

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An inhibitor of USP7 (IC50 = 0.75 µM); selective for USP7 over USP47 and USP5 (IC50s = 20.3 and >200 µM, respectively); enhances ubiquitination of the USP7 substrate MDM2 in HCT116 colon cancer cells (IC50 = 0.23 µM); reduces cell viability in a panel of 108 cell lines (IC50s = <10 µM for all); enhances apoptosis induced by doxorubicin or cisplatin in MCF-7 and U2OS cancer cells, respectively

Catalog No. 50-294-9807


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