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Cayman Chemical ANTIBODY GR79236 1mg
Supplier: Cayman Chemical 284301 MG
A selective adenosine A1 receptor agonist (Kis = 3.1 and 1,300 nM for adenosine A1 and A2 receptors, respectively, in rat brain; inhibits isoprenaline-induced cAMP accumulation in DDT1MF-2 hamster smooth muscle cells (IC50 = 2.6 nM) but only decreases contractility in isolated guinea pig atria with an EC50 value of 1,500 nM; inhibits norepinephrine-induced lipolysis in rat adipocytes (EC50 = 0.83 nM); decreases locomotor activity and inhibits DMCM-induced seizures in mice (ED50s = 0.13 and 0.3 mg/kg, respectively); decreases blood pressure by 74% in anesthetized rats at 0.1 mg/kg
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