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Cayman Chemical ANTIBODY GW 806742X 25mg
Supplier: Cayman Chemical 3754125 MG
An inhibitor of necroptosis; binds to Mlkl (Kd = 9.3 µM for the mouse protein) and decreases necroptosis induced by TNF-α, a Smac mimetic, and Q-VD-OPH in isolated mouse dermal fibroblasts at 500 nM; an inhibitor of VEGFR2 (IC50 = 2 nM); decreases VEGF-induced proliferation of HUVECs (IC50 = 5 nM); inhibits mammosphere formation by, reduces the number of extracellular actin fibers extruding from, and decreases intracellular IL-1β levels in, MDA-MB-231 cancer cells at 10 µM
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