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Cayman Chemical ANTIBODY HT-2157 5mg
Supplier: Cayman Chemical 338485 MG
A GAL3 receptor antagonist (Ki = 17 nM); selective for GAL3 over GAL1 and GAL2 (Kis = >10 µM for both); induces apoptosis in various cell types, including HL-60 leukemia and BV-2 murine microglial cells, as well as isolated human PBMCs at 10 µM; decreases operant alcohol, sucrose, and saccharin self-administration in rats at 30 mg/kg; increases drinking in the Vogel punished drinking task and reduces immobility time in the forced swim test in rats, indicating anxiolytic- and antidepressant-like activities, respectively, at 3 and 10 mg/kg
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