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Cayman Chemical ANTIBODY IM-93 10mg
Supplier: Cayman Chemical 2879410 MG
A dual inhibitor of ferroptosis and NETosis; inhibits tert-butyl hydroperoxide- and erastin-induced ferroptosis in NIH3T3 cells (IC50s =1.8 and 1.9 nM, respectively), as well as decreases PMA-induced NETosis and lipid peroxidation in isolated human peripheral blood neutrophils at 1.6-25 µM; inhibits hydrogen peroxide-induced necrosis in HL-60 cells (IC50 = 0.45 µM), but has no effect on necroptosis induced by Fas ligand in combination with Z-VAD-FMK and cycloheximide in Jurkat cells or pyroptosis induced by S. aureus and P. aeruginosa in THP-1 cells at 25 µM
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