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Cayman Chemical ANTIBODY JAK3-IN-2 25mg
SDP

Supplier:  Cayman Chemical 3734425 MG

Encompass_Preferred

A JAK3 inhibitor (Ki = 0.07 nM); selective for JAK3 over JAK1 and JAK2 (Kis = 320 and 740 nM, respectively); inhibits IL-2-induced STAT5 gene expression in a reporter assay (IC50 = 70 nM); reduces paw swelling and ankle bone loss in a rat model of collagen-induced arthritis at 100, 300, and 600 mg/kg

Catalog No. 50-291-5211


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