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Cayman Chemical ANTIBODY JYL1421 1mg
Supplier: Cayman Chemical 204581 MG
A TRPV1 antagonist; inhibits capsaicin-induced calcium uptake in CHO cells expressing rat TRPV1 (EC50 = 9.2 nM); inhibits capsaicin-induced release of somatostatin, substance P, and CGRP from isolated rat trachea (IC50s = 227-491 nM); inhibits capsaicin-induced hypothermia and hypotension in rats at 2 and 0.4 mg/kg, respectively; reduces the number of wiping movements induced by ocular administration of capsaicin in rats at 2 mg/kg
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