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Cayman Chemical ANTIBODY KB-130015 25mg
Supplier: Cayman Chemical 3346125 MG
An antiarrhythmic agent; inhibits acetylcholine or adenosine-induced potassium currents in isolated guinea pig atrial myocytes (IC50s = 0.82 and 0.57 µM, respectively); activates or inhibits hERG in a voltage-dependent manner; activates KCa1.1/BKCa channels in HEK293 cells expressing Slo1 (EC50 = 20.2 µM); prolongs the duration of electrically stimulated action potentials in guinea pig papillary muscle ex vivo at 40 mg/kg; a TRα and TRβ antagonist (IC50s = 2.2 and 4.1 µM, respectively, in reporter assays)
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