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Cayman Chemical ANTIBODY LEE011 25mg
Supplier: Cayman Chemical 1766625 MG
A selective cyclin D1/CDK4 and cyclin D3/CDK6 inhibitor (nm IC50) that inhibits retinoblastoma protein phosphorylation, which prevents CDK-mediated G1-S phase transition, arresting the cell cycle in the G1 phase, suppressing DNA synthesis, and inhibiting cancer cell growth; reduces proliferation of several human neuroblastoma-derived cell lines (mean IC50 = 306 nM)
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