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Cayman Chemical ANTIBODY LSN2814617 1mg
Supplier: Cayman Chemical 336071 MG
A positive allosteric modulator of mGluR5 receptors; potentiates glutamate-induced calcium mobilization in MCB3901 cells expressing human mGluR5 (EC50 = 52 nM); increases rat hippocampal mGluR5 receptor occupancy (ED50 = 13 mg/kg); increases wakefulness and decreases NREM and REM sleep in rats at 0.3, 1, and 3 mg/kg
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