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Cayman Chemical ANTIBODY LSN3318839 500ug
Supplier: Cayman Chemical 41245500 UG
A positive allosteric modulator of GLP-1R; potentiates increases in cAMP accumulation induced by GLP-1 (9-36) in INS-1 832/3 cells; increases insulin levels in the presence, but not absence, of GLP-1 (9-36) in INS-1 832/3 cells under high-glucose conditions at 1 and 3 µM; reduces blood glucose levels in GIPR knockout mice in an oral glucose tolerance test at 30 mg/kg; has an additive effect on reducing blood glucose levels in GIPR knockout mice at 10 or 30 mg/kg in combination with sitagliptin
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