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Cayman Chemical ANTIBODY Lu AE58054 25mg
Supplier: Cayman Chemical 2733525 MG
A 5-HT6 receptor antagonist (Ki = 0.83 nM); selective for 5-HT6 over other 5-HT receptor subtypes (Kis = 250 to >10,000 nM) and 70 other targets but does bind to α1A- and α1B-ARs (Kis = 21 and 22 nM, respectively); reverses phencyclidine-induced deficits in novel object recognition memory in rats at 5-20 mg/kg; has an additive effect on the decreased number of slips and falls made by rats in a dual-lesion model of Parkinson’s disease motor disruption when administered in combination with rivastigmine
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