Cayman Chemical ANTIBODY MasItInIb 25mg

Supplier:  Cayman Chemical 1310525 MG

An inhibitor of c-Kit (IC50 = 200 nM); an inhibitor of PDGFRα, PDGFRβ, and Lyn B (IC50s = 540, 800, and 510 nM, respectively); inhibits stem cell factor-induced proliferation of Ba/F3 cells expressing wild-type KIT (IC50 = 150 nM), as well as those expressing the KIT mutants KITV559D and KITΔ27 (IC50s = 3 and 5 nM, respectively); an inhibitor of SARS-CoV-2 Mpro (Ki = 2.6 µM); inhibits replication of SARS-CoV-2 in infected A549 cells (EC50 = 3.2 µM); decreases lung and nose viral titers, as well as reduces lung inflammation and increases survival, in ACE2-humanized mice infected with SARS-CoV-2 at 25 mg/kg

Catalog No. 50-295-4151