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Cayman Chemical ANTIBODY MB-07811 1mg
Supplier: Cayman Chemical 306701 MG
A liver-targeted prodrug of MB-07344; binds to TRα1 and TRβ1 (Kis = 12.5 and 14.6 µM, respectively); reduces plasma cholesterol levels (ED50 = 0.48 mg/kg) in a cholesterol-fed rat model; reduces hepatic steatosis, as well as plasma levels of cholesterol, in Zucker diabetic fatty rats in a model of NAFLD at 5 mg/kg per day; reverses hepatic steatosis, reducing total hepatic lipids without decreasing body weight, in a mouse model of diet-induced obesity at 10 mg/kg
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