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Cayman Chemical ANTIBODY MK-1775 5mg
Supplier: Cayman Chemical 212665 MG
An inhibitor of the checkpoint kinase Wee1 (IC50 = 5.2 nM) that prevents phosphorylation of Cdc2 at tryosine15, which abrogates the G2 DNA damage checkpoint; induces apoptosis in combination with several DNA damaging agents selectively in p53-deficient tumor cell lines
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