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Cayman Chemical ANTIBODY MnIdIpIn 10mg
Supplier: Cayman Chemical 2361410 MG
An L- and T-type calcium channel blocker; blocks recombinant rabbit L-type (α1Cα2/δβ1a) and human T-type (α1H) calcium channels expressed in Xenopus oocytes; blocks native L-type channels in dissociated guinea pig cardiac ventricular cells (IC50 = 2.6 nM); inhibits ET-1-induced increases in intracellular calcium in A7r5 rat vascular smooth muscle cells (ED50 = 1 nM); inhibits potassium-induced contraction of isolated dog femoral and portal veins (IC50s = 24 and 2.1 nM, respectively); lowers blood pressure in SHRs (10 mg/kg); inhibits isoproterenol-induced left ventricular hypertrophy in rats (3 mg/kg)
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