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Cayman Chemical ANTIBODY MRS1754 25mg
Supplier: Cayman Chemical 3350125 MG
An adenosine A2B receptor antagonist (Ki = 1.97 nM); selective for adenosine A2B receptors over adenosine A1, A2A, and A3 receptors (Kis = 403, 503, and 570 nM, respectively); increases 28-day survival, as well as decreases peritoneal bacterial growth and plasma levels of IL-6, TNF-α, and MIP-2, in a mouse model of CLP-induced sepsis from 0.5-10 mg/kg; reduces disease severity in a mouse model of EAE at 1 mg/kg
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