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Cayman Chemical ANTIBODY NG-497 5mg
Supplier: Cayman Chemical 368865 MG
An ATGL inhibitor (IC50 = 1 µM); selective for ATGL over PNPLA1, PNPLA3, PNPLA4, and PNPLA5 at 100 µM; selectively inhibits the triacylglycerol hydrolase activity of human and rhesus monkey ATGL over rat, dog, and marmoset ATGL, which it inhibits by less than 20% at 50 µM, and over mouse, goat, and pig ATGL at which it is inactive at 50 µM; inhibits isoproterenol-induced fatty acid and glycerol release in human SGBS adipocytes (IC50 = 1.5 µM for both)
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