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Cayman Chemical ANTIBODY NS 5806 5mg

Supplier: Cayman Chemical 332265 MG
An Ito current activator; increases Kv4.3-mediated Ito current amplitudes (EC50 = 5.3 µM), as well as slows Ito current decay in a KChIP2-dependent manner, in CHO-K1 cells expressing human KV4.3; increases Ito currents in isolated rabbit ventricular myocytes (EC50 = 1.6 µM); reverses rapid pacing-induced decreases in Ito current recovery and restores the spike-and-dome morphology of the epicardial action potential in ventricular wedge preparations isolated from a dog model of heart failure
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