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Cayman Chemical ANTIBODY PAP-1 1mg
Supplier: Cayman Chemical 301051 MG
An inhibitor of Kv1.3 channels (EC50 = 2 nM at -80 mV in cells overexpressing the human channel); selective for Kv1.3 over a panel of 22 ion channels (EC50s = 45-15,000 nM for all); inhibits anti-CD3 antibody-induced proliferation of isolated human CCR7- effector memory T cells; inhibits ovalbumin-induced delayed-type hypersensitivity in rats at 3 mg/kg
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