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Cayman Chemical ANTIBODY PD 0325901 5mg
Supplier: Cayman Chemical 130345 MG
A potent MEK inhibitor that suppresses phosphorylation of ERK in murine colon 26 tumors with an IC50 value of 0.33 nM; suppression of ERK activation with 1 µM PD 0325901 combined with 3 µM CHIR99021 (a glycogen synthase kinase-3 inhibitor) prevents cell differentiation and sustains self renewal of mouse embryonic stem cells for at least eight passages
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